Carprofen

Chemical name: (+/-)-6-chloro-alpha-methylcarbazole-2-acetic acidMolecular formula: C₁₅H₁₂ClNO₂Molecular weight: 273.71CAS: 53716-49-7Structural formula:

Specification:A: In-house specification Combin ation of specification in USP and EP）Appearance: White or off-white crystalline powderLoss on drying (USP): ≤0.5%Residue on ignition (USP): ≤0.1%Assay (calculated on dried substance) (USP): 98.0~102.0%Carbazole（USP）: ≤0.5%Ketal（USP）: ≤0.5%6-chloro- biacetylcarbazole (USP): ≤0.5%Any individual unspecified impurity(USP): ≤0.10%Total impurities(USP): ≤1.0%Total aerobic microbial count: ≤100cfu/gTotal yeast and mold count: ≤50cfu/gBacterial endotoxins: ＜0.25EU/mgB: In accordance with EPAppearance: White or off-white crystalline powderLoss on drying: ≤0.5%Sulfated ash: ≤0.1%Any individual unspecified impurity: ≤0.20%Total impurities: ≤0.5%Heavy metal: ≤20ppmAssay: 98.5~101.5%C: Specification for Veterinary drugCharacters: White or off-white crystalline powder. Freely soluble in acetone and methanol, slightly soluble in isopropyl alcohol, practically insoluble in water.Loss on drying: ≤0.5%Residue on ignition: ≤0.1%Heavy metal: ≤20ppmCarbazole: ≤0.5%Ketal: ≤0.5%6-chloro- biacetylcarbazole: ≤0.5%Any individual unspecified impurity: ≤0.10%Total impurities: ≤1.0%Assay: 98.0~102.0%Packing size: 25Kg/drumIndications: It has strong anti-inflammatory, analgesic and antipyretic effects, used for rheumatoid arthritis, osteoarthritis, acute gout, tendonitis, bursitis, soft tissue off injury or acute pain after surgical operation or a wound.